Science
2023
14th Netherlands Conference on HIV Pathogenesis, Epidemiology, Prevention and Treatment (NCHIV)
Exploring and comparing Biomarker Profiles and Comorbidity burden in people with and without HIV: A Latent Profile Analysis of the AGEhIV Cohort Study
Presented by: Manon Vanbellinghen
The Dutch Association of HIV-treating physicians (NVHB), winter meeting
Similar cellular immune responses after SARS-CoV-2 vaccination in older people with well-controlled HIV and demographically and lifestyle-comparable controls without HIV
Presented by: Myrthe Verburgh
2022
HIV Glasgow
Older people with well-controlled HIV have similar antibody and higher T-cell responses after vaccination against SARS-CoV-2 compared to demographically and lifestyle-comparable controls without HIV
Presented by: Myrthe Verburgh
2021
14th Netherlands Conference on HIV Pathogenesis, Epidemiology, Prevention and Treatment (NCHIV)
People with HIV and suppressed viremia on ART are not at increased risk for acquiring SARS-CoV-2 infection
Presented by: Myrthe Verburgh
2020
13th Netherlands Conference on HIV Pathogenesis, Epidemiology, Prevention and Treatment (NCHIV)
Faster decline in lung function in treated HIV-positive vs. HIV-negative AGEhIV cohort participants independent of smoking behavior
Presented by: Sebastiaan Verboeket
22nd International Workshop on Co-morbidities and Adverse Drug Reactions in HIV
Faster decline in lung function in treated HIV-positive vs. HIV-negative AGEhIV cohort participants independent of smoking behavior
Presented by: Sebastiaan Verboeket
Selective drop-out of HIV-positive AGEhIV Cohort participants may bias estimates of long-term adverse health effects of ageing with HIV
Presented by: Eveline Verheij
2019
International Workshop on HIV Observational Databases (IWHOD)
Development and validation of an index to assess the comorbidity burden of people living with HIV
Presented by: Davide de Francesco
Conference on Retroviruses and Opportunistic Infections (CROI)
Impact and determinants of comorbidity clusters in people living with HIV
Presented by: Davide de Francesco
The Dutch Association of HIV-treating physicians (NVHB), mid-summer meeting
Switchen naar een antiretroviraal regime met een integraseremmer in het AGEhIV Cohort is niet geassocieerd met een bovengemiddelde toename in lichaamsgewicht
Presented by: Sebastiaan Verboeket
21st International Workshop on Co-morbidities and Adverse Drug Reactions in HIV
Colonic microbiota exhibits disparate associations with HIV-infection and sexual practices
Presented by: Eveline Verheij
Switching to an integrase inhibitor containing antiretroviral regimen is not associated with above-average weight gain in middle-aged people living with HIV on long-term suppressive antiretroviral therapy, the AGEhIV cohort study
Presented by: Sebastiaan Verboeket
Development and validation of an index to assess the comorbidity burden of people living with HIV
Presented by: Davide De Francesco
17th European AIDS Conference (EACS)
Colonic microbiota exhibits disparate associations with HIV-infection and sexual practices
Presented by: Eveline Verheij
Switching to an integrase inhibitor containing antiretroviral regimen is not associated with above-average weight gain in middle-aged people living with HIV on long-term suppressive antiretroviral therapy, the AGEhIV cohort study
Presented by: Sebastiaan Verboeket
Development and validation of an index to assess the comorbidity burden of people living with HIV
Presented by: Davide De Francesco
2018
International Workshop on HIV Observational Databases (IWHOD)
Pulmonary function in controlled HIV-infection: lower forced vital capacity but similar 1-second forced expiratory volume among those with limited smoking experience
Presented by: Sebastiaan Verboeket
International Symposium on HIV and Emerging Infectious Diseases (ISHEID)
Dealing with multimorbidities in HIV
Presented by: Rosan van Zoest
International AIDS Conference
Heterogeneity in pulmonary function indices by HIV status and cumulative smoking intensity among well-controlled HIV-infected persons compared to HIV-uninfected participants in the AGEhIV cohort
Presented by: Sebastiaan Verboeket
Increased risk of both mortality and incident comorbidity among frail HIV-positive and HIV-negative participants in the AGEhIV cohort study, and increased risk of frailty progression in those with HIV
Presented by: Eveline Verheij
Congrès VIH Complications et Comorbidités
AGEhIV cohort update
Presented by: Rosan van Zoest
International Workshop on Co-morbidities and Adverse Drug Reactions in HIV
HIV-negative men who have sex with men have lower CD4 to CD8 ratios driven by higher absolute CD8 T-lymphocyte counts compared to HIV-negative heterosexual men
Presented by: Sebastiaan Verboeket
2017
16th European AIDS Conference
HIV and Ageing: Using Cohort Data to Separate the Myths from Reality
Presented by: Rosan van Zoest
19th Bangkok International Symposium on HIV Medicine
Co- and multi-morbidity in people ageing with HIV
Presented by: Peter Reiss
Conference on Retroviruses and Opportunistic Infections (CROI)
Longitudinal analysis shows no evidence for accelerated brain ageing in treated HIV
Presented by: Rosan van Zoest
The Dutch Association of HIV-treating physicians (NVHB), winter meeting
Brain grey and white matter (micro)structural abnormalities in successfully treated HIV infection most likely reflect historical injury
Presented by: Rosan van Zoest
Hiv-infectie is onafhankelijk geassocieerd met verminderde erectiele functie onder mannen van middelbare leeftijd die seks hebben met mannen
Presented by: Maartje Dijkstra
International Workshop on HIV Observational Databases (IWHOD)
HIV-1 status is independently associated with decreased erectile function among middle-aged men who have sex with men
Presented by: Maartje Dijkstra
WEON
HIV-1 status is independently associated with decreased erectile function among middle-aged men who have sex with men
Presented by: Maartje Dijkstra
International AIDS Society Conference
HIV-1 status is independently associated with decreased erectile function among middle-aged men who have sex with men
Presented by: Maartje Dijkstra
People living with HIV and HIV-negative individuals with similar lifestyles show greater age advancement compared to healthy blood donors
Presented by: Davide de Francesco
2016
International Workshop on HIV Observational Databases
HIV infection is independently associated with chronic kidney disease and mild glomerular hyperfiltration, particularly in those of African descent
Presented by: Katherine Kooij
Primary and secondary cardiovascular prevention is suboptimal in both HIV-infected and HIV-uninfected participants of the AGEhIV Cohort Study
Presented by: Rosan van Zoest
The Dutch Association of HIV-treating physicians (NVHB), summer meeting
Primary and secondary cardiovascular prevention is suboptimal in both HIV-infected and HIV-uninfected participants of the AGEhIV Cohort Study
Presented by: Rosan van Zoest
International Workshop on Co-morbidities and Adverse Drug Reactions in HIV
Primary and secondary cardiovascular prevention is suboptimal in both HIV-infected and HIV-uninfected participants of the AGEhIV Cohort Study
Presented by: Rosan van Zoest
Link
Netherlands Conference on HIV Pathogenesis, Epidemiology, Prevention and Treatment
HIV infection is independently associated with chronic kidney disease and mild glomerular hyperfiltration, particularly in those of African descent
Presented by: Katherine Kooij
Link
Prise en charge clinique du sujet âgé vivant avec le VIH, Marseille
Elderly & HIV: Results from the AGEhIV Cohort Study
Presented by: Rosan van Zoest
European HIV Nursing Conference
The impact of the number of co-morbidities and aging on Health Related Quality of Life in HIV-infected and uninfected individuals
Presented by: Nienke Langebeek
2015
The Dutch Association of HIV-treating physicians (NVHB), winter meeting
Performance of 4 Tools to Screen for HIV-Associated Cognitive Impairment.
Presented by: Rosan van Zoest
Highlights in Basic and Clinical Science (HIBIC) conference
Low BMD in patients with well-suppressed HIV infection.
Presented by: Katherine Kooij
Conference on Retroviruses and Opportunistic Infections
Performance of 4 Tools to Screen for HIV-Associated Cognitive Impairment.
Presented by: Rosan van Zoest
Link
APRI and FIB4: Associated With D-Drug Exposure, Low CD4 Count and Monocyte Activation
Presented by: Katherine Kooij
Link
International Workshop on HIV Observational Databases
Frailty predicts all-cause mortality, hospital admission and falls in HIV-infected and -uninfected middle-aged individuals
Presented by: Katherine Kooij/Ferdinand Wit
Higher prevalence of hypertension in HIV-infected individuals partially explained by increased waist-hip ration rather than BMI, other traditional risk factors or markers of systemic inflammation
Presented by: Rosan van Zoest
Nederlands Oogheelkundig Gezelschap (NOG)
Structureel en functioneel oogheelkundig onderzoek bij HIV-positieve patienten
Presented by: Nazli Demirkaya
Association for Research in Visual Science and Opthalmology (ARVO)
Visual function and corneal endothelium analysis in patients with well-suppressed HIV infection
Presented by: Nazli Demirkaya
The Dutch Association of HIV-treating physicians (NVHB) summer meeting
Hogere prevalentie van hypertensie onder hiv-geïinfecteerden grotendeels verklaard door abdominale obesitas en stavudine-gerelateerde lipoatrofie
Presented by: Rosan van Zoest
European AIDS Clinical Society
Increased prevalence of hypertension in HIV-infected patients, most with suppressed viraemia on combination antiretroviral therapy, is associated with changes in body composition
Presented by: Rosan van Zoest
Link
Frailty predicts all-cause mortality, hospital admission and falls in HIV-infected and uninfected middle-aged individuals
Presented by: Katherine Kooij
Link
MAPPING Workshop MICCAI
A neuroscience gateway for handling and processing population imaging studies
Presented by: Matthan Caan
Link
Assessment of Resources and Opportunities for NeuroAIDS Research
Prevalence of NCI in the Netherlands
Presented by: Judith Schouten
Link
3e Landelijk Valsymposium
Frailty voorspelt mortaliteit, ziekenhuisopname en vallen in hiv-geïnfecteerde en ongeïnfecteerde mensen van middelbare leeftijd
Presented by: Katherine Kooij
Link
Netherlands Conference on HIV Pathogenesis, Epidemiology, Prevention and Treatment
The impact of the number of comorbidities and aging on Health Related Quality of Life in HIV-infected and uninfected individuals
Presented by: Nienke Langebeek
Link
VII Congreso Nacional GeSIDA
HIV, Co-morbidity and Ageing
Presented by: Peter Reiss
Link
2014
Conference on Retroviruses and Opportunistic Infections (CROI)
Multivariate normative comparison, a novel method for more reliably detecting cognitive impairment in HIV infection.
Presented by: Judith Schouten
ISMRM Benelux Chapter
White Matter Abnormalities in Males with Suppressed HIV-infectiono n cART compared to representative controls.
Presented by: Tanja Su
International Workshop on HIV Observational Databases
HIV infection is independently associated with frailty in middle aged HIV infected individuals compared to uninfected controls
Presented by: Katherine Kooij
Dutch Ophthalmic Society Conference
Neuroretinal degeneration in HIV-positive patients
Presented by: Nazli Demirkaya
Innsbruck HIV Update
Comorbidity and ageing in HIV-1 infection: The AGEhIV Cohort Study
Presented by: Peter Reiss
HIV Drug Therapies in the Americas
Co-morbidities and Ageing in HIV
Presented by: Peter Reiss
Association for Research in Visual Science and Opthalmology
Neuroretinal degeneration in HIV-positive patients
Presented by: Nazli Demirkaya
Joint Annual Meeting ISMRM-ESMRMB
White Matter Abnormalities in Males with Suppressed HIV-infectiono n cART compared to representative controls
Presented by: Tanja Su
WEON
Prevalence and determinants of insufficient work ability in older HIV-positive and HIV-negative workers
Presented by: Lisanne Moller
International Symposium on Neurobiology and Neuroendocrinology of Aging
Multivariate normative comparison, a novel method for more reliably detecting cognitive impairment in HIV infection
Presented by: Judith Schouten
HIV infection is independently associated with frailty in middle aged HIV infected individuals compared to uninfected controls
Presented by: Katherine Kooij
White Matter Abnormalities in Adequately treated HIV-infection
Presented by: Tanja Su
Immune activation and immunosenescence in HIV infection.
Presented by: Neeltje Kootstra
International AIDS Conference
Prevalence and determinants of insufficient work ability in older HIV-positive and HIV-negative workers
Presented by: Ronald Brands
Disentangling Biological Aging, the Inflammatory Effects of Long Term HIV infection and Adverse Effects of ART
Presented by: Peter Reiss
International Workshop on Co-morbidities and Adverse Drug Reactions in HIV
Higher prevalence of hypertension in HIV-infected patients partially explained by increased waist-hip ratio rather than BMI, other traditional risk factors or markers of systemic inflammation.
Presented by: Rosan van Zoest
Netherlands Conference on HIV Pathogenesis, Epidemiology, Prevention and Treatment
HIV infection is independently associated with frailty in middle-aged HIV-infected individuals compared to uninfected controls.
Presented by: Katherine Kooij
Higher prevalence of hypertension in HIV-infected individuals partially explained by increased waist-hip ratio rather than BMI, other traditional risk factors or markers of systemic inflammation.
Presented by: Rosan van Zoest
Accentuated CD8+ T-cell senescence is associated with both age and CD8+ T cell activation in long-term treated HIV-1 infected patients.
Presented by: Viviana Cobos Jiménez
Prevalence and determinants of insufficient work ability in older HIV-positive and HIV-negative workers.
Presented by: Lisanne Moller
2013
International Workshop on HIV Observational Databases
Prevalence and determinants of reduced bone mineral density in ageing HIV-1-positive and HIV-negative individuals.
Presented by: Katherine Kooij
The Dutch Association of HIV-treating physicians (NVHB), spring meeting
Prevalence and determinants of reduced bone mineral density in ageing HIV-1-positive and HIV-negative individuals.
Presented by: Katherine Kooij
International Neuropsychological Society Mid-Year Meeting
Neuropsychological and Neuroimaging Status of Middle-aged HIV-infected Males with Suppressed Infection on cART Compared to a Respresentative Control Group.
Presented by: Tanja Su
AIDS Impact Conference
Prevalence and determinants of non-participation in paid work among ageing HIV-1 infected and HIV-uninfected individuals.
Presented by: Ineke Stolte
European AIDS Clinical Society (EACS) Conference
Prevalence and determinants of reduced bone mineral density in ageing HIV-1-positive and HIV-negative individuals.
Presented by: Katherine Kooij
Greater arterial stiffness in middle-aged HIV-1-positive individuals largely explained by higher prevalence of hypertension and smoking.
Presented by: Katherine Kooij
International Workshop on Co-morbidities and Adverse Drug Reactions in HIV
Prevalence and determinants of reduced bone mineral density in ageing HIV-1-positive and HIV-negative individuals.
Presented by: Katherine Kooij
Netherlands Conference on HIV Pathogenesis, Epidemiology, Prevention and Treatment
Calendar age predicts CD8+ T-cell senescence in long-term treated HIV-infected patients but not in HIV-uninfected controls.
Presented by: Maaike Joerink
Najaarsvergadering NVVI
Calendar age predicts CD8+ T-cell senescence in long-term treated HIV-infected patients but not in HIV-uninfected controls.
Presented by: Maaike Joerink
Annual meeting of the Netherlands Ophthalmological Society (NOG)
Baseline ophthalmological results substudy AGEhIV.
Presented by: Nazli Demirkaya
Annual meeting of the Association for Research in Vision and Opthalmology (ARVO)
Baseline ophthalmological results substudy AGEhIV.
Presented by: Nazli Demirkaya
2012
International Workshop on HIV Observational Databases
Comorbidity and ageing with HIV A prospective comparative cohort study.
Presented by: Judith Schouten
International Workshop on Co-morbidities and Adverse Drug Reactions in HIV
Comorbidity and ageing with HIV A prospective comparative cohort study.
Presented by: Judith Schouten
International AIDS Conference (IAS)
Comorbidity and ageing with HIV A prospective comparative cohort study.
Presented by: Judith Schouten
Netherlands Conference on HIV Pathogenesis, Epidemiology, Prevention and Treatment
Prevalence and determinants of unemployment among ageing HIV-1 infected and HIV-uninfected individuals.
Presented by: Ineke Stolte
International Congress on Drug Therapy in HIV
Prevalence and determinants of unemployment among ageing HIV-1 infected and HIV-uninfected individuals.
Presented by: Ineke Stolte
2011
Netherlands Conference on HIV Pathogenesis, Epidemiology, Prevention and Treatment
Comorbidity and ageing with HIV A prospective comparative cohort study.
Presented by: Judith Schouten
2023
No association between use of tenofovir disoproxil fumarate, etravirine, or integrase-strand transfer inhibitors and acquisition or severe outcomes of SARS-CoV-2 infection in people with HIV in the Netherlands.
Verburgh ML, Van der Valk M, Rijnders BJA, Reiss P, Wit FWNM
AIDS. 2023 Jul 15;37(9):1481-1486
Link
Robust Vaccine-Induced as Well as Hybrid B- and T-Cell Immunity across SARS-CoV-2 Vaccine Platforms in People with HIV
Verburgh ML*, Van Pul L*, Grobben M*, Boyd A, Wit FWNM, Van Nuenen AC, Van Dort KA, Tejjani K, Van Rijswijk J, Bakker M, Van der Hoek L, Schim van der Loeff MF, Van der Valk M, Van Gils MJ*, Kootstra NA*, Reiss P*; for the AGEhIV Study Group.* Authors contributed equally
Microbiol Spectr. 2023 Jun 15;11(3):e0115523.
Link
Long-term evolution of comorbidities and their disease burden in individuals with and without HIV as they age: analysis of the prospective AGEhIV cohort study.
Verheij E, Boyd A, Wit FW, Verboeket SO, Verburgh ML, Van der Valk M, Schim van der Loeff MF, Reiss P; on behalf of the AGEhIV cohort study
Lancet HIV. 2023 Mar;10(3):e164-e174.
Link
2022
Change in Substance Use and the Effects of Social Distancing on Health-Related Quality of Life and Depressive Symptoms During the COVID-19 Pandemic in People Living With and Without HIV
Schaaf, Reja E. A.; Verburgh, Myrthe L.; Boyd, Anders; Wit, Ferdinand W.; Nieuwkerk, Pythia T.; Schim van der Loeff, Maarten F.; Reiss, Peter; for the AGEhIV Study Group.
JAIDS Journal of Acquired Immune Deficiency Syndromes. 2022, 91(3):p 261-268
Link
The experienced positive and negative influence of HIV on quality of life of people with HIV and vulnerable to HIV in the Netherlands
Romijnders KAGJ, de Groot L, Vervoort SCJM, Basten M, van Welzen BJ, Kretzschmar ME, Reiss P, Davidovich U, van der Loeff MFS, Rozhnova G.
Sci Rep. 2022 Dec 19;12(1):21887
Link
2021
Similar risk of SARS-CoV-2 infection and similar nucleocapsid antibody levels in people with well-controlled HIV and a comparable cohort of people without HIV
Myrthe L. Verburgh, Anders Boyd, Ferdinand W.N.M. Wit, Maarten F. Schim van der Loeff, Marc van der Valk, Margreet Bakker, Neeltje A. Kootstra, Lia van der Hoek and Peter Reiss; on behalf of the AGEhIV Cohort Study Group.
J Infect Dis. 2021; online ahead of print.
Link
The Complement Pathway Is Activated in People With Human Immunodeficiency Virus and Is Associated With Non-AIDS Comorbidities
Vujkovic-Cvijin I, Sortino O, Verheij E, Wit FW, Kootstra NA, Sellers B, Schim van der Loeff M, Belkaid Y, Reiss P, Sereti I.
J Infect Dis. 2021; 224(8): 1405-1409
Link
Generally rare but occasionally severe weight gain after switching to an integrase inhibitor in virally suppressed AGEhIV cohort participants
Sebastiaan O. Verboeket, Anders Boyd, Ferdinand W. Wit, Eveline Verheij, Maarten F. Schim van der Loeff, Neeltje Kootstra, Marc van der Valk, Peter Reiss, on behalf of the AGEhIV Cohort Study Group.
PLoS One. 2021; 16(5): e0251205.
Link
Changes in lung function among treated HIV-positive and HIV-negative individuals: analysis of the prospective AGEhIV cohort study
Sebastiaan O. Verboeket, Anders Boyd, Ferdinand W. Wit, Eveline Verheij, Maarten F. Schim van der Loeff, Neeltje Kootstra, Marc van der Valk, Reindert P. van Steenwijk, Bradley Drummond, Gregory D. Kirk, Peter Reiss; on behalf of the AGEhIV Cohort Study.
Lancet Healthy Longev. 2021; 2: e202-11.
2020
Human Immunodeficiency Virus (HIV)-Negative Men Who Have Sex With Men Have Higher CD8+ T-Cell Counts and Lower CD4+/CD8+ T-Cell Ratios Compared With HIV-Negative Heterosexual Men
Sebastiaan O. Verboeket, Ferdinand W. Wit, Eveline Verheij, Rosan A. van Zoest, Neeltje A. Kootstra, Marc van der Valk, Jan M. Prins, Maarten F. Schim van der Loeff, and Peter Reiss; on behalf of the AGEhIV Study Group.
J Infect Dis 2020 Jan 31;jiaa048.
Link
Frailty is associated with mortality and incident comorbidity among middle-aged HIV-positive and HIV-negative participants
Verheij. E, Kirk. GD, Wit. FW, van Zoest. RA, Verboeket. SO, Lemkes. BA, Schim van der Loeff. MF, Reiss. P, for the AGEhIV Cohort
J Infect Dis 2020 Aug 17;222(6):919-928.
Link
HIV-associated gut dysbiosis is independent of sexual practice and correlates with noncommunicable diseases
I. Vujkovic-Cvijin, O. Sortino, E. Verheij, J. Sklar, F. W. Wit, N. A. Kootstra, B. Sellers, J. M. Brenchley, J. Ananworanich, M. Schim van der Loeff, Y. Belkaid, P. Reiss & I. Sereti
Nature Communications 2020 May 15;11(1):2448.
Link
Frequency, risk factors and mediators of frailty transitions during long-term follow-up among people with HIV and HIV-negative AGEhIV Cohort participants
Verheij. E, Wit. FW, Verboeket. SO, Schim van der Loeff. MF, Nellen. JF, Reiss. P, Kirk. GD
J Acquir Immune Defic Syndr 2020 Jan 1;86(1):110-118.
Link
2019
Reduced Forced Vital Capacity among HIV-infected middle-aged individuals
Verboeket SO, Wit FW, Kirk GD, Drummond MB, van Steenwijk RP, van Zoest RA, Nellen JF, van der Loeff MFS, Reiss P.
J Infect Dis 2019 Apr 8;219(8):1274-1284.
Link
Validation of a Novel Multivariate Method of Defining HIV-Associated Cognitive Impairment
Underwood J, De Francesco D, Cole JH, Caan MWA, van Zoest RA, Schmand BA, Sharp DJ, Sabin CA, Reiss P, Winston A; COmorBidity in Relation to AIDS (COBRA) Collaboration and the Pharmacokinetic and clinical Observations in PeoPle over fiftY (POPPY) Study Group.
Open Forum Infect Dis. 2019 May 3;6(6):ofz198.
Link
Cognitive function and drivers of cognitive impairment in a European and a Korean cohort of people living with HIV
De Francesco D, Jae-phil Choi, Jun Yong Choi, Rosan A. van Zoest, Jonathan Underwood, Judith Schouten, Nam Su Ku, Woo Joo Kim, Peter Reiss, Caroline A. Sabin and Alan Winston on behalf of the ComorBidity in Relation to AIDS (COBRA) Collaboration and the Korean NeuroAIDS Project.
Int J STD AIDS. 2019 Dec 4:956462419881080.
Link
2018
HIV-1 status is independently associated with decreased erectile function among middle-aged MSM in the era of combination antiretroviral therapy.
Dijkstra M, van Lunsen RHW, Kooij KW, Davidovich U, van Zoest RA, Wit FWMN, Prins M, Reiss P, Schim van der Loeff MF; AGEhIV Cohort Study Group.
AIDS. 2018; 32: 1137-1146.
Link
Clinical research cerebral MRI findings in HIV-positive subjects and appropriate controls.
Chhabra S, Underwood J, Cole JH, Caan M, Waldman A, Reiss P, Sabin CA, Sharp DJ, Winston A; CoBRA collaboration.
AIDS. 2018; 32: 2077-2081.
Link
The ‘COmorBidity in Relation to AIDS’ (COBRA) cohort: Design, methods and participant characteristics.
De Francesco D, Wit FW, Cole JH, Kootstra NA, Winston A, Sabin CA, Underwood J, van Zoest RA, Schouten J, Kooij KW, Prins M, Guaraldi G, Caan MWA, Burger D, Franceschi C, Libert C, Bürkle A, Reiss P; COmorBidity in Relation to AIDS (COBRA) collaboration.
PLoS One. 2018; 13: e0191791.
Link
No Evidence for Accelerated Aging-Related Brain Pathology in Treated Human Immunodeficiency Virus: Longitudinal Neuroimaging Results From the Comorbidity in Relation to AIDS (COBRA) Project.
Cole JH, Caan MWA, Underwood J, De Francesco D, van Zoest RA, Wit FWNM, Mutsaerts HJMM, Leech R, Geurtsen GJ, Portegies P, Majoie CBLM, Schim van der Loeff MF, Sabin CA, Reiss P, Winston A, Sharp DJ; Comorbidity in Relations to AIDS (COBRA) Collaboration.
Clin Infect Dis. 2018; 66: 1899-1909.
Link
Patterns of Co-occurring Comorbidities in People Living With HIV.
Francesco D, Verboeket SO, Underwood J, Bagkeris E, Wit FW, Mallon PWG, Winston A, Reiss P, Sabin CA; Pharmacokinetic and Clinical Observations in PeoPle Over fiftY (POPPY) study and the AGEhIV Cohort Study.
Open Forum Infect Dis. 2018 Oct 24;5(11):ofy272.
Link
2017
High Cellular Monocyte Activation in People Living With Human Immunodeficiency Virus on Combination Antiretroviral Therapy and Lifestyle-Matched Controls Is Associated With Greater Inflammation in Cerebrospinal Fluid.
Booiman T, Wit FW, Maurer I, De Francesco D, Sabin CA, Harskamp AM, Prins M, Garagnani P, Pirazzini C, Franceschi C, Fuchs D, Gisslén M, Winston A, Reiss P, Kootstra NA; Comorbidity in Relation to AIDS (COBRA) Collaboration.
Open Forum Infect Dis. 2017; 4: ofx108.
Link
Structural brain abnormalities in successfully treated HIV infection: associations with disease and cerebrospinal fluid biomarkers.
Van Zoest RA, Underwood J, De Francesco D, Sabin CA, Cole JH, Wit FW, Caan MWA, Kootstra NA, Fuchs D, Zetterberg H, Majoie CBLM, Portegies P, Winston A, Sharp DJ, Gisslén M, Reiss P; Co-morBidity in Relation to AIDS (COBRA) Collaboration.
J Infect Dis. 2017; 217: 69-81.
Link
Higher Prevalence and Faster Progression of Chronic Kidney Disease in Human Immunodeficiency Virus–Infected Middle-Aged Individuals Compared With Human Immunodeficiency Virus–Uninfected Controls.
Kooij KW, Vogt L, Wit FW, van der Valk M, van Zoest RA, Goorhuis A, Prins M, Post FA, Reiss P, on behalf of the AGEhIV Cohort Study.
J Infect Dis. 2017; 216: 622-631.
Link
Suboptimal primary and secondary cardiovascular disease prevention in HIV-positive individuals on antiretroviral therapy.
van Zoest RA, van der Valk M, Wit FW, Vaartjes I, Kooij KW, Hovius JW, Prins M, Reiss P; AGEhIV Cohort Study Group.
Eur J Prev Cardiol. 2017; 24: 1297-1307.
Link
Grey and white matter abnormalities in treated HIV-disease and their relationship to cognitive function.
Underwood J, Cole JH, Caan M, De Francesco D, Leech R, van Zoest RA, Su T, Geurtsen GJ, Schmand BA, Portegies P, Prins M, Wit FW, Sabin CA, Majoie C, Reiss P, Winston A, Sharp DJ; Co-morBidity in Relation to Aids (COBRA) Collaboration.
Clin Infect Dis. 2017; 65: 422-432.
Link
Increased brain-predicted aging in treated HIV disease.
Cole JH, Underwood J, Caan MW, De Francesco D, van Zoest RA, Leech R, Wit FW, Portegies P, Geurtsen GJ, Schmand BA, Schim van der Loeff MF, Franceschi C, Sabin CA, Majoie CB, Winston A, Reiss P, Sharp DJ; COBRA collaboration.
Neurology. 2017; 88: 1349-1357.
Link
Impact of comorbidity and aging on health-related quality of life in HIV-positive and HIV-negative individuals.
Langebeek N, Kooij KW, Wit FW, Stolte IG, Sprangers MAG, Reiss P, Nieuwkerk PT: AGEhIV Study Group
AIDS. 2017; 31: 1471-1481.
Link
3D scattering transforms for disease classification in neuroimaging
T. Adel, T. Cohen, M. Caan, M. Welling; AGEhIV Study Group and the Alzheimer’s Disease Neuroimaging Initiative
Neuroimage Clin. 2017; 14: 506-17.
Link
Cerebral blood flow and cognitive function in HIV-infected men with sustained suppressed viremia on combination antiretroviral therapy
Tanja Su, HJ Mutsaerts, Matthan Caan, Ferdinand Wit, Judith Schouten, Gert Geurtsen, David Sharp, Maria Prins, Edo Richard, Peter Portegies, Peter Reiss, Charles Majoie, on behalf of the AGEhIV Cohort Study
AIDS. 2017; 31: 847-56.
Link
2016
Cigarette Smoking and Inflammation, Monocyte Activation, and Coagulation in HIV-Infected Individuals Receiving Antiretroviral Therapy, Compared With Uninfected Individuals
Katherine Kooij, Ferdinand Wit, Thijs Booiman, Marc van der Valk, Maarten Schim van der Loeff, Neeltje Kootstra, Peter Reiss; AGEhIV Cohort Study Group.
J Infect Dis. 2016; 214: 1817-21.
Link
White matter structure alterations in HIV-1-infected men with sustained suppression of viraemia on treatment
Tanja Su, Matthan Caan, Ferdinand Wit, Judith Schouten, Gert Geurtsen, James Cole, David Sharp, Frans Vos, Maria Prins, Peter Portegies, Peter Reiss, Charles Majoie
AIDS. 2016; 30: 311-22.
Link
HIV infection is independently associated with frailty in middle-aged HIV type 1-infected individuals compared with similar but uninfected controls
Katherine Kooij, Ferdinand Wit, Judith Schouten, Marc van der Valk, Mieke Godfried, Ineke Stolte, Maria Prins, Julian Falutz, Peter Reiss
AIDS, 2016; 30: 241-50.
Link
Determinants of reduced cognitive performance in HIV-1-infected middle-aged men on combination antiretroviral therapy.
Judith Schouten, Tanja Su, Ferdinand Wit, Neeltje Kootstra, Matthan Caan, Gert Geurtsen, Ben Schmand, Ineke Stolte, Maria Prins, Charles Majoie, Peter Portegies, Peter Reiss
AIDS, 2016; 30: 1027-38.
Link
Prevalence and determinants of insufficient work ability in older HIV-positive and HIV-negative workers.
Lisanne Moller, Ronald Brands, Judith Sluiter, Judith Schouten, Ferdinand Wit, Peter Reiss, Maria Prins, Ineke Stolte.
Int Arch Occup Environ Health, 2016; 89: 699-709.
Link
HIV-associated Neuroretinal Disorder in Patients with Well-suppressed HIV-infection: A Comparative Cohort Study.
Nazli Demirkaya, Ferdinand Wit, Thomas van den Berg, Katherine Kooij, Maria Prins, Reinier Schlingemann, Michael Abramoff, Peter Reiss, Frank Verbraak.
Invest Ophthalmol Vis Sci, 2016; 57: 1388-97.
Link
Difference in aortic stiffness between treated middle-aged HIV type 1-infected and uninfected individuals largely explained by traditional cardiovascular risk factors, with an additional contribution of prior advanced immunodeficiency.
Katherine Kooij*, Judith Schouten*, Ferdinand Wit, Marc van der Valk, Neeltje Kootstra, Ineke Stolte, Jan van der Meer, Maria Prins, Diederick Grobbee, Bert-Jan van den Born, Peter Reiss.
J Acquir Immune Defic Syndr. 2016; 73: 55-62.
Link
Liver fibrosis in HIV-infected individuals on long-term antiretroviral therapy: associated with immune activation, immunodeficiency and prior use of didanosine.
Katherine Kooij, Ferdinand Wit, Rosan van Zoest, Judith Schouten, Neeltje Kootstra, Michele van Vugt,
Maria Prins, Peter Reiss, Marc van der Valk.
AIDS. 2016; 30: 1771-80.
Link
Higher prevalence of hypertension in HIV-1-infected patients on combination antiretroviral therapy is associated with changes in body composition and prior stavudine exposure.
Rosan van Zoest, Ferdinand Wit, Katherine Kooij, Marc van der Valk, Judith Schouten, Neeltje Kootstra, Joost Wiersinga, Maria Prins, Bert-Jan van den Born, Peter Reiss.
Clinical Infectious Diseases, 2016; 63: 205-13.
Link
T-Cell Activation Independently Associates With Immune Senescence in HIV-Infected Recipients of Long-term Antiretroviral Treatment.
Viviana Cobos Jiménez, Ferdinand Wit, Maaike Joerink, Irma Maurer, Agnes Harskamp, Judith Schouten, Maria Prins, van Leeuwen EM, Thijs Booiman, Steven Deeks, Peter Reiss, Neeltje Kootstra.
Journal of Infectious Diseases, 2016; 214: 216-25.
Link
White matter hyperintensities in relation to cognition in HIV-infected men with sustained suppressed viral load on cART.
Tanja Su, Ferdinand Wit, Matthan Caan, Judith Schouten, Maria Prins, Gert Geurtsen, James Cole, David Sharp, Edo Richard, Liesbeth Reneman, Peter Portegies, Peter Reiss, Charles Majoie.
AIDS. 2016; 30: 2329-39.
Link
2015
Multivariate normative comparison, a novel method for more reliably detecting cognitive impairment in HIV infection.
Tanja Su, Judith Schouten, Gert Geurtsen, Ferdinand Wit, Ineke Stolte, Maria Prins, Peter Portegies, Matthan Caan, Peter Reiss, Charles Majoie, Ben Schmand; AGEhIV Cohort Study Group.
AIDS. 2015;29:547-57.
Link
Low bone mineral density in patients with well-suppressed HIV infection: association with body weight, smoking, and prior advanced HIV disease.
Katherine Kooij, Ferdinand Wit, Peter Bisschop, Judith Schouten, Ineke Stolte, Maria Prins, Marc van der Valk, Jan Prins, Berthe van Eck-Smit, Paul Lips, Peter Reiss; AGEhIV Cohort Study Group.
J Infect Dis. 2015; 211: 539-48.
Link
2014
Cross-sectional comparison of the prevalence of age-associated comorbidities and their risk factors between HIV-infected and uninfected individuals: the AGEhIV cohort study.
Judith Schouten, Ferdinand Wit, Ineke Stolte, Neeltje Kootstra, Marc van der Valk, Suzanne Geerlings, Maria Prins, Peter Reiss; AGEhIV Cohort Study Group.
Clin Infect Dis. 2014;59:1787-97.
Link
Data Sharing
We endeavour to make the data used in any AGEhIV Cohort Study manuscript publicly available, within the limits of the ethical governance under which the data were collected. To this end, we will share data directly with interested parties for two purposes: 1) verification and replication of an already published analysis derived from the AGEhIV Cohort Study, 2) novel scientific research projects using AGEhIV Cohort Study data.
To facilitate this, requests for data sharing can be made on a case-by-case basis following submission of a concept sheet. Once submitted the proposed research/analysis will undergo review by the AGEhIV Cohort Study team for evaluation of the scientific value, relevance to the study, design and feasibility, statistical power and overlap with existing projects. If the proposed analysis is for verification/replication, data will then be made available. If the proposed research is for novel science, upon completion of the review, feedback will be provided to the proposer(s). In some circumstances, a revision of the concept may be requested. If the concept is approved for implementation, a writing group will be established consisting of the proposers (up to 3 persons that were centrally involved in the development of the concept) and members of the AGEhIV Cohort Study group (or other appointed cohort representatives). All persons involved in the process of reviewing these research concepts are bound by confidentiality.
For more information about the procedure, data sharing or collaboration in general, please contact Ms. Lilly Dol (l.dol@aighd.org).
